PSTReader

Program for Reading Parent-Sibling Tracing (PST) 

Parent-Sibling Tracing: a Method to Explore the Meiotic Recombination Event in Humans

IBD: Three generation pedigree

IBS: Identity by state (reference: PLoS ONE; August 2009 | Volume 4 | Issue 8 | e6711)

PediSNP (reference: BMC Medical Genetics 2009, 10:93 doi:10.1186/1471-2350-10-93)

PST: Parent-sibling identity Tracing

 

 

User Manual

 

 

 

Manuscript

 

 

 

Program

 

 

 

Data and Results

    1. GMRCL 900K

             Data

             Results

    2. Autism 10k

             Data

             Results

 

 

 

Calling schema for

        TGP

        PediSNP

        PST

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Parent-Sibling Tracing: a Method to Explore the Meiotic Recombination Event in Humans

Yun-Shien Lee1,2, Chun-Houh Chen3, Tina Chou3, Angel Chao4, and Tzu-Hao Wang2, 4

1Department of Biotechnology, Ming Chuan University, Tao-Yuan, Taiwan

2Genomic Medicine Research Core Laboratory, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan

3Institute of Statistical Science, Academia Sinica, Taipei, Taiwan

4Department of Obstetrics and Gynecology, Lin-Kou Medical Center, Chang Gung Memorial Hospital and Chang Gung University, Tao-Yuan, Taiwan

 

ABSTRACT

Meiotic recombination is a key mechanism for generating genetic diversity. In meiosis, crossovers result in genetic exchanges that provide daughter cells with new combinations of parental alleles.

 

 

 

keywords: Meiosis, bioinformatics.

 

Note: PSTReader is an open source program which means you are free to use and modify it by your own interests. Also, you are ready to take the risk of errors and bugs inside the program.

Webpage Produce by: Tina Chou